Figure 3
Residues in colicin–immunity protein complexes that are predicted to contribute to inter-molecular interactions in the E7-like family and the Im7-like family. (A,B) Residue-level sequence maps summarizing the structure-based energy calculations for the complexes of immunity proteins (A) with their cognate colicins/pyocins (B). Residues that contribute substantially to interactions are colored according to the type of their energy contribution: non-polar contributions (np), green; side-chain electrostatic contributions (sc elec), red; main-chain electrostatic contributions (mc elec), yellow; sc elec and mc elec, orange; sc elec and np, magenta; mc elec and np, cyan; sc elec, mc elec and np, purple. Immunity protein and colicin/pyocin positions are numbered according Im7 (Im7#) and Col-E7 (E7#) and together with the Im7/Col-E7 secondary structure elements are shown above and below the alignment.
