Table 4 Cox regression model analysis for prediction of progression-free survival

From: Differential expression of PD-L1 between primary and metastatic epithelial ovarian cancer and its clinico-pathological correlation

Clinico-pathological variables

Progression-free survival

Univariate

Multivariate

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value

Age

Above > 50 years (vs ≤ 50 years)

1.13 (0.80–1.61)

0.4795

1.24 (0.85–1.81)

0.2673

Histologic grade

High grade (vs. low grade)

1.01 (0.67–1.57)

0.9547

0.83 (0.53–1.33)

0.4304

Lymph node metastasis

N1 (vs. N0)

0.95 (0.51–1.63)

0.8651

1.04 (0.52–1.92)

0.8999

Stage

IV (vs. I–III)

1.93 (1.25–2.89)

0.0035

2.14 (1.34–3.32)

0.0017

Residual tumor

Present (vs. Absent)

1.25 (0.88–1.77)

0.2141

1.37 (0.94–1.98)

0.0972

PD-L1 (Primary tumor)

High (vs. Low)

1.07 (0.73–1.54)

0.7318

1.13 (0.74–1.71)

0.5548

PD-L1 (Peritoneal metastases)

High (vs. Low)

0.89 (0.63–1.27)

0.5340

0.93 (0.62–1.38)

0.7180

  1. (Significant p values are highlighted in bold)