Table 3 Multivariable linear regression analysis of predictors for biomarkers of ageing among patients with pulmonary tuberculosis.
From: Telomere length and outcome of treatment for pulmonary tuberculosis in a gold mining community
Variables | Leukocyte telomere length | Mitochondrial DNA content | ||
|---|---|---|---|---|
Percent difference (95% CI) | p-value | Percent difference (95% CI) | p-value | |
Age (+ 1 year) | − 0.85 (− 1.19 to − 0.52) | < 0.0001 | − 0.21 (− 0.55 to 0.14) | 0.24 |
Sex | ||||
Female | Ref | |||
Male | 6.07 (− 3.2 to 14.51) | 0.19 | 1.02 (− 8.31 to 11.32) | 0.83 |
BMI (+ 1 kg/m2) | 1.25 (− 1.22 to 3.78) | 0.32 | 2.57 (0.05–5.24) | 0.05 |
Mining-related activities | ||||
No | Ref | |||
Yes | − 9.99 (− 21.15 to 0.14) | 0.05 | 3.85 (− 5.96 to 14.68) | 0.45 |
Tobacco smoking | ||||
No | Ref | |||
Yes | − 11.87 (− 31.64 to 4.94) | 0.18 | − 14.67(− 27.72 to 0.76) | 0.06 |
Tuberculosis category | ||||
New case | Ref | |||
Retreatment | − 7.11 (− 22.06 to 6.01) | 0.30 | 1.38 (− 11.35 to 15.95) | 0.84 |
HIV (+) | ||||
No | Ref | |||
Yes | − 14.24 (− 28.22 to − 1.79) | 0.02 | − 4.72 (− 15.5 to 7.43) | 0.43 |
