Table 3 Cox proportional hazard analyses for cardiovascular death in tertiles of FABP4 (n = 721).

From: Elevated circulating FABP4 concentration predicts cardiovascular death in a general population: a 12-year prospective study

 

Model 1

Model 2

Model 3

Model 4

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

FABP4

T1

Reference

Reference

Reference

Reference

T2

2.71 (0.59–12.5)

0.201

2.76 (0.59–12.9)

0.196

2.15 (0.44–10.5)

0.344

2.07 (0.42–10.2)

0.372

T3

4.98 (1.15–21.6)

0.032

5.38 (1.21–23.8)

0.028

4.96 (1.10–22.3)

0.037

4.83 (1.06–21.9)

0.041

Age (per 1 year)

1.08 (1.03–1.14)

< 0.001

1.09 (1.05–1.13)

< 0.001

1.09 (1.04–1.13)

< 0.001

1.08 (1.03–1.13)

0.001

Sex (male)

1.95 (0.68–5.62)

0.214

1.98 (0.69–5.71)

0.205

2.10 (0.71–6.27)

0.180

2.29 (0.76–6.89)

0.141

Interaction*

 

0.951

 

0.955

 

0.940

 

0.962

Body mass index

0.91 (0.86–0.97)

0.002

0.90 (0.85–0.97)

0.001

0.91 (0.86–0.98)

0.005

BNP (per 1 pg/mL)

1.01 (1.00–1.01)

< 0.001

1.01 (1.00–1.01)

< 0.001

1.01 (1.00–1.01)

< 0.001

hsCRP (per 1 mg/dL)

1.25 (0.01–49.4)

0.915

1.07 (0.01–41.7)

0.975

Smoking habit

0.85 (0.27–2.65)

0.778

Hypertension

1.89 (0.61–5.81)

0.267

Diabetes mellitus

0.44 (0.10–1.94)

0.281

Dyslipidemia

0.90 (0.42–1.96)

0.800

 

(AIC = 384)

 

(AIC = 366)

 

(AIC = 323)

 

(AIC = 329)

 
  1. *Interaction: Sex—FABP4 tertiles.
  2. AIC Akaike's information criterion, BNP brain natriuretic peptide, CI confidence interval, FABP4 fatty acid-binding protein 4, HR hazard ratio, hsCRP high-sensitivity C-reactive protein.