Table 2 Patient characteristics.

Participant number	Age	Gender	BMI	Years since diagnosis	Therapy	Total units of insulin injection per day	Total units of insulin injection per day/BW (kg)	HbA1c (%) of baseline	Fasting serum CPR (ng/ml)
1	46.4	Female	18.1	1.3	MDI	20.0	0.43	7.4	0.277
2	74.2	Female	14.9	13.3	MDI	27.0	0.86	9.5	< 0.01
3	61.7	Male	29.7	19.3	CSII	48.2	0.66	9.3	< 0.01
4	70.7	Female	22.0	25.8	CSII	51.6	1.04	7.4	< 0.01
5	34.2	Female	25.0	1.2	CSII	48.0	0.82	6.5	< 0.01
6	70.5	Female	20.6	30.8	MDI	32.0	0.69	6.4	< 0.01
7	70.9	Female	20.3	23.8	MDI	8.0	0.18	6.3	1.21
8	55.2	Female	20.3	0.7	MDI	23.0	0.44	6.7	1.13
9	38.4	Female	23.6	3.8	CSII	25.5	0.39	8.6	< 0.01
10	30.5	Male	27.9	14.8	CSII	50.2	0.63	11.5	< 0.01
11	32.3	Female	21.0	0.6	CSII	32.5	0.76	7.5	< 0.01
12	62.3	Male	19.6	1.4	MDI	33.0	0.53	7.2	0.311
13	39.0	Female	18.9	0.9	CSII	34.0	0.74	6.2	0.409
14	42.6	Male	27.5	9.0	MDI	53.0	0.65	7.2	< 0.01
15	43.2	Male	23.0	3.6	CSII	30.4	0.45	7.7	0.318
16	63.1	Female	16.8	4.0	MDI	17.0	0.42	7.3	0.064
17	53.1	Male	23.2	1.9	MDI	15.0	0.19	6.7	0.931
18	75.8	Female	21.1	5.0	MDI	18.0	0.37	8.2	0.285
19	45.3	Female	19.1	6.3	CSII	26.0	0.55	7.2	0.030
Total or mean ± SD	53.1 ± 15.2	Female: 13, Male: 6	21.7 ± 3.8	8.8 ± 9.6	MDI: 10, CSII: 9	31.2 ± 13.5	0.57 ± 0.22	7.6 ± 1.3	0.261 ± 0.397^a

BMI body mass index, BW body weight, CPR C-peptide immunoreactivity, CSII continuous subcutaneous insulin infusion, MDI multiple dose insulin injection.
^aThe values of serum CPR “ < 0.01” were considered as 0 and calculated. Fasting CPR was measured on at least three different dates and the value on the day closest to the baseline date were adopted.

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