Table 4 Comparison between vaccine nonavalent and quadrivalent, considering all positive HPV patients and all subgroups defined in this study.

From: Potential impact of a nonavalent anti HPV vaccine in Italian men with and without clinical manifestations

 

Vaccine quadrivalent genotype

Vaccine nonavalent genotype

Quadrivalent vs. Nonavalent

p-value (p)

All HPV positive patients (572)

Vaccine impact

Low Impact

19.8% (113/572)

29.7% (170/572)

19.8% < 29.7%, p* < 0.0001 (M)

High Impact

26.6% (152/572)

34.6% (198/572)

26.6% < 34.6%, p* < 0.0001 (M)

Group I

138 positive HPV patients

Vaccine impact

 Low Impact

29.7% (41/138)

35.5% (49/138)

29.7% < 35.5%, p* = 0.0078 (M)

 High Impact

28.3% (39/138)

32.6% (45/138)

28.3% < 32.6%, p = 0.146 (M)

Group II

137 positive HPV patients

Vaccine impact

 Low Impact

19.7% (27/137)

31.4% (43/137)

19.7% < 31.4%, p* < 0.0001 (M)

 High Impact

31.4% (43/137)

38% (52/137)

31.4% < 38%, p = 0.0931 (M)

Group III

297 positive HPV patients

Vaccine impact

 Low Impact

15.1% (45/297)

26.3% (78/297)

15.1% < 26.3%, p* < 0.0001 (M)

 High Impact

23.2% (69/297)

33.7% (100/297)

23.2% < 33.7%, p* < 0.0001 (M)

  1. *Significant test; M McNemar exact test.