Table 2 Antimicrobial resistance-conferring genes identified in the HS-MSSA genome.
AMR gene | Contig | Region position (bp) | SNP | Genomic region | Drug class | AMR gene family |
|---|---|---|---|---|---|---|
arlS | 7 | 73,606–74,961 | – | Chromosome | Fluoroquinolone antibiotic; acridine dye | Major facilitator superfamily (MFS) antibiotic efflux pump |
arlR | 7 | 74,958–75,617 | – | Chromosome | Fluoroquinolone antibiotic; acridine dye | Major facilitator superfamily (MFS) antibiotic efflux pump |
norA | 16 | 13,813–14,979 | – | Chromosome | Fluoroquinolone antibiotic | Major facilitator superfamily (MFS) antibiotic efflux pump |
mgrA | 16 | 22,630–23,073 | – | Chromosome | Fluoroquinolone antibiotic; cephalosporin; penam; tetracycline antibiotic; peptide antibiotic; acridine dye | ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump |
lmrS | 21 | 40,760–42,205 | – | Chromosome | Macrolide antibiotic; aminoglycoside antibiotic; oxazolidinone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic | Major facilitator superfamily (MFS) antibiotic efflux pump |
mepR | 32 | 38,133–38,552 | – | Chromosome | Glycylcycline; tetracycline antibiotic | Multidrug and toxic compound extrusion (MATE) transporter |
mepA | 32 | 38,659–40,014 | – | Chromosome | Glycylcycline; tetracycline antibiotic | Multidrug and toxic compound extrusion (MATE) transporter |
blaZ | 33 | 4979–5824 | – | Plasmid | Penam | blaZ beta-lactamase |
tet(38) | 43 | 1800–3158 | – | Chromosome | Tetracycline antibiotic | Major facilitator superfamily (MFS) antibiotic efflux pump |
GlpT variant | 32 | 40,641–41,999 | A100V | Chromosome | Fosfomycin | GlpT |
