Figure 1
From: Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens
Backbone overlay of the 20 NMR solution structures with the lowest energy of the four hazelnut allergens Cor a 1.0401 (a), Cor a 1.0402 (b), Cor a 1.0403 (c), and Cor a 1.0404 (d), with the PDB codes 6Y3H, 6Y3I, 6Y3K, and 6Y3L, respectively. The secondary structure elements are defined as β1 (Val2–Ser11), α1 (Pro15–Leu24), α2 (Ala26–Ala34), β2 (Thr39–Glu45), β3 (Gly51–Ala59), β4 (Phe64–Asp75), β5 (Phe79–Glu87), β6 (Glu96–Ala106), β7 (Gly112–Thr123), and α3 (Glu131–His155). The α-helices are highlighted in red, β-strands in blue, and loops in light gray. Loops L1–L9 as well as N- and C-termini are indicated.
