Table 3 Active genes and their corresponding signal pathways they participate in after PPI analysis with PXR.
From: Bioinformatis analysis reveals possible molecular mechanism of PXR on regulating ulcerative colitis
Gene symbol | Gene name | Signal pathway |
|---|---|---|
PCK1 | phosphoenolpyruvate carboxykinase 1 | GLUCONEOGENESIS |
PPARGC1A | PPARG Coactivator 1 Alpha | INSULIN_PATHWAY |
CES2 | Carboxylesterase 2 | DRUG_METABOLISM_OTHER_ENZYMES |
ABCG2 | ATP Binding Cassette Subfamily G Member 2 | ABC_TRANSPORTERS |
CYP2B6 | Cytochrome P450 Family 2 Subfamily B Member 6 | METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450 |
CXCL8 | C-X-C Motif Chemokine Ligand 8 | TOLL-LIKE_RECEPTOR_SIGNALING_PATHWAY |
CYTOKINE-CYTOKINE_RECEPTOR_INTERACTION | Â | Â |
