Table 1 FIC index of interactions between the peptide and first- and second-line anti-TB drugs.

From: A broad spectrum anti-bacterial peptide with an adjunct potential for tuberculosis chemotherapy

Drug combinationsa

FIC indexb

Interpretation

NZX: RIF

2.1

Indifference

NZX: EMB

0.75

Additive

NZX: INH

1

Additive

NZX: AMK

1.1

Indifference

  1. aNZX (peptide), RIF (rifampicin), INH (isoniazid), EMB (ethambutol), AMK (amikacin).
  2. bFIC Index borders: synergistic (≤ 0.5), additive (> 0.5–1), indifference (1–4), antagonistic (> 4).
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