Table 5 Estimates of parameters in RBE model (Eq. 5) based on Poisson regression that includes all observed data, both pre- and post-flight with separate terms for sensitivity to gamma radiation (\({\beta }_{1,pre}\)) and BFO dose (\({\beta }_{1,post}\)) as well as overall age and gender effects.

From: Predicting chromosome damage in astronauts participating in international space station missions

RBE model parameter

Equation (5) predictor variable

Est

SE

Z-value

p

β1,pre

xpre,ij

4.031

0.14

28.7

 < 0.001

β1,post

xpost,ij

12.475

1.058

11.8

 < 0.001

β2

A50i

0.027

0.011

2.4

0.018

β3

Fi

0.153

0.11

1.4

0.164

β0

1

 − 5.679

0.064

 − 89.3

 < 0.001

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