Table 1 Baseline demographics and aneurysm characteristics of patients with unruptured and ruptured anterior communicating (ACoA) aneurysms (N = 505).
Unruptured ACoA aneurysms (N = 274) | Ruptured ACoA aneurysms (N = 231) | Total (N = 505) | P value | |
|---|---|---|---|---|
Patient characteristics | ||||
Age at presentation (mean ± SD) | 61 ± 12 | 54 ± 13 | 57 ± 13 | < 0.01 |
Female (%) | 174 (64) | 135 (58) | 309 (62) | 0.25 |
Current tobacco use (%) | 74 (28) | 95 (38) | 169 (34) | < 0.01 |
Tobacco use > 1 pack per day (%) | 16 (5.8) | 21 (9.1) | 37 (7.3) | 0.16 |
Years since quit tobacco (SD) | 9.5 (22.4) | 21.5 (26.9) | 20.6 (26.7) | 0.10 |
Current alcohol use (%) | 114 (45) | 122 (57) | 236 (51) | 0.01 |
Hypertension (%) | 153 (56) | 124 (54) | 277 (55) | 0.63 |
Atrial fibrillation* | 0 (0) | 5 (2.4) | 5 (2.2) | 0.51 |
History of ischemic stroke* | 0 (0) | 16 (7.6) | 16 (7.0) | 0.23 |
Coronary artery disease* | 0 (0) | 11 (5.2) | 11 (4.8) | 0.32 |
History of myocardial infarction (%)* | 0 (0) | 8 (3.8) | 8 (3.5) | 0.40 |
Family history of SAH (%) | 24 (9) | 15 (7) | 39 (8) | 0.32 |
Family history of intracranial aneurysm (%) | 47 (17) | 28 (12) | 75 (15) | 0.10 |
Aspirin use at diagnosis (%)* | 0 (0) | 26 (12.3) | 26 (11.4) | 0.11 |
Anticoagulant use at diagnosis (%)* | 0 (0) | 5 (2.4) | 5 (2.2) | 0.51 |
Antihyperlipidemic agent use at diagnosis (%)* | 1 (5.6) | 36 (17.1) | 37 (16.2) | 0.20 |
Intrinsic morphological parameters | ||||
Projection (%) | 0.04 | |||
Anterior (Ref) | 222 (81) | 202 (87) | 424 (84) | |
Posterior | 15 (5.5) | 13 (5.6) | 28 (5.5) | |
Superior | 19 (6.9) | 9 (3.9) | 28 (5.5) | |
Inferior | 18 (6.6) | 7 (3.0) | 25 (5.0) | |
Location (%) | 0.23 | |||
Medial (Ref) | 26 (9.5) | 17 (7.4) | 43 (8.5) | |
Left | 149 (54) | 120 (52) | 269 (53) | |
Right | 99 (36) | 94 (41) | 193 (38) | |
Irregularity (%) | 46 (18) | 125 (54) | 171 (34) | < 0.01 |
Daughter dome (%) | 40 (15) | 160 (69) | 200 (40) | < 0.01 |
Maximum height (mm ± SD) | 4.7 ± 2.6 | 5.7 ± 2.6 | 5.1 ± 2.6 | < 0.01 |
Perpendicular height (mm ± SD) | 4.3 ± 2.4 | 5.2 ± 2.5 | 4.7 ± 2.5 | < 0.01 |
Neck diameter (mm ± SD) | 3.9 ± 1.4 | 3.3 ± 1.3 | 3.6 ± 1.4 | < 0.01 |
Width (mm ± SD) | 4.5 ± 2.2 | 4.5 ± 2.3 | 4.5 ± 2.3 | 0.98 |
Height/width ratio | 0.95 ± 0.3 | 1.2 ± 0.4 | 1.1 ± 0.3 | < 0.01 |
Aspect ratio | 1.1 ± 0.5 | 1.6 ± 0.6 | 1.3 ± 0.6 | < 0.01 |
Transitional morphological parameters | ||||
Size ratio | 0.73 ± 0.4 | 0.92 ± 0.4 | 0.82 ± 0.4 | < 0.01 |
Flow angle | 125 ± 21 | 136 ± 22 | 130 ± 22 | < 0.01 |
Extrinsic morphological parameters | ||||
Pre-aneurysm A1 length (mm) | 16 ± 2.3 | 16 ± 2.2 | 16 ± 2.2 | 0.67 |
ACoA diameter (mm) | 1.6 ± 0.5 | 1.6 ± 0.5 | 1.6 ± 0.5 | 0.50 |
Ipsilateral A1 diameter (mm) | 1.9 ± 0.4 | 1.8 ± 0.4 | 1.9 ± 0.4 | < 0.01 |
Ipsilateral A2 diameter (mm) | 1.9 ± 0.4 | 1.8 ± 0.4 | 1.8 ± 0.4 | < 0.01 |
Contralateral A1 diameter (mm) | 0.98 ± 0.7 | 0.95 ± 0.6 | 0.97 ± 0.6 | 0.34 |
Contralateral A2 diameter (mm) | 1.9 ± 0.4 | 1.8 ± 0.4 | 1.8 ± 0.4 | 0.11 |
Hypoplastic A1 | 111 (41) | 85 (37) | 196 (39) | 0.39 |
Aplastic A1 | 62 (23) | 50 (22) | 112 (22) | 0.79 |
Ipsilateral A1-A2 angle | 99 ± 25 | 105 ± 1.4 | 102 ± 1.0 | < 0.01 |
Ipsilateral A1-ACoA angle | 103 ± 22 | 100 ± 20 | 102 ± 21 | 0.06 |
Ipsilateral A2-ACoA angle | 131 ± 27 | 125 ± 21 | 128 ± 24 | 0.01 |
Contralateral A1-A2 angle | 111 ± 24 | 116 ± 22 | 113 ± 24 | 0.09 |
Contralateral A1-ACoA angle | 109 ± 21 | 110 ± 21 | 109 ± 21 | 0.93 |
Contralateral A2-ACoA angle | 116 ± 22 | 111 ± 20 | 113 ± 21 | 0.04 |
