Table 4 Results of ANCOVA analysis of rs894280, and global cognition and the five cognitive domains.

From: Investigating the relationship between the SNCA gene and cognitive abilities in idiopathic Parkinson’s disease using machine learning

Cognitive domain

Mean, SD, (Min–Max)

CC

N = 33

CT/TT

N = 68

CI95% rs894280

Significance

Global cognition

0, ± 0.5, (− 1, 1)

− 0.4, ± 0.6, (− 2, 1)

0.006–0.42a

0.04*

Attention

0, ± 0.5, (− 1, 1)

− 0.4, ± 0.6, (− 1, 1)

0.12–0.56a

0.003**

Executive function

− 0.3, ± 0.7, (− 2, 1)

− 0.5 ± 0.9, (− 3, 1)

− 0.10–0.55a

0.19

Language

0, ± 0.7, (− 1, 1)

− 0.2, ± 0.8, (− 2, 1)

− 0.16 – 0.44a

0.36

Memory

0.2, ± 0.7, (− 1, 1)

− 0.3, ± 0.8, (− 2, 1)

0.07–0.70a

0.02

Visuo-spatial

− 0.1, ± 0.6, (− 2, 1)

− 0.6, ± 1, (− 3, 1)

0.16–0.87b

0.005**

  1. SD = Standard Deviation, CI 95% = 95% confidence intervals.
  2. aUPDRS-III, Education, R rostral-anterior cingulate and L middle temporal thickness measures were entered in the model.
  3. bUPDRS-III, Education, R rostral-anterior cingulate and L middle temporal thickness measures and EHI score were entered in the model.
  4. *Significance level was set to 0.05.
  5. **Significance level was set to 0.01, Bonferroni correction.