Table 3 Sex differences in the multivariable Cox regression analysis in the original and the propensity score-matched cohorts of patients with HCM.

From: Sex differences in the prognosis of patients with hypertrophic cardiomyopathy

Variables

Unadjusted

Model 1a

Model 2b

Propensity score-matched

HR for women (95% CI)

p

HR for women (95% CI)

p

HR for women (95% CI)

p

HR for women (95% CI)

p

Primary endpoint

1.49 (1.30–1.71)

< 0.001

1.39 (1.21–1.60)

< 0.001

1.43 (1.24–1.64)

< 0.001

1.43 (1.22–1.68)

< 0.001

Cardiovascular death

1.18 (0.88–1.59)

0.266

1.07 (0.80–1.44)

0.645

1.11 (0.83–1.50)

0.478

1.27 (0.91–1.78)

0.162

New-onset HF admission

1.63 (1.41–1.89)

< 0.001

1.53 (1.31–1.77)

< 0.001

1.55 (1.34–1.80)

< 0.001

1.54 (1.30–1.82)

< 0.001

All-cause death

0.93 (0.73–1.18)

0.546

0.82 (0.64–1.05)

0.118

0.83 (0.65–1.07)

0.144

0.91 (0.69–1.21)

0.525

  1. HCM hypertrophic cardiomyopathy, HR hazard ratio, HF heart failure.
  2. aMultivariate clinical model 1 was adjusted for age and Charlson comorbidity index.
  3. bModel 2 was adjusted for age, Charlson comorbidity index, low income, hypertension, dyslipidemia, ischemic heart disease requiring coronary intervention, chronic kidney disease, atrial fibrillation, and beta-blocker.
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