Table 3 Accuracy of new Corvis ST parameters in identifying SKC and KC eyes.

From: Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population

Parameters

AUC (95%CI)

Youden index

Cut off

Sensitivity (%)

Specificity (%)

SKC versus control

Max inverse radius

0.626 (0.555, 0.693)

0.23

 > 0.19

50

73

DA ratio max (2 mm)

0.684 (0.615, 0.748)

0.33

 > 4.47

81

52

Pachy slope

0.538 (0.466, 0.608)

0.16

 > 44.30

46

70

DA ratio max (1 mm)

0.673 (0.603, 0.737)

0.31

 > 1.60

80

51

ARTh

0.618 (0.547, 0.686)

0.30

 ≤ 434.02

51

79

Integrated radius

0.668 (0.598, 0.733)

0.33

 > 8.94

81

52

SP-A1

0.753 (0.687, 0.811)

0.40

 ≤ 107.30

66

74

CBI

0.703 (0.635, 0.766)

0.38

 > 0.05

56

82

KC versus SKC

Max inverse radius

0.889 (0.837, 0.929)

0.65

 > 0.20

87

78

DA ratio max (2 mm)

0.903 (0.853, 0.940)

0.69

 > 5.29

80

89

Pachy slope

0.908 (0.859, 0.944)

0.69

 > 55.49

73

96

DA ratio max (1 mm)

0.843 (0.785, 0.891)

0.61

 > 1.67

79

82

ARTh

0.980 (0.949, 0.994)

0.88

 ≤ 319.83

89

99

Integrated radius

0.932 (0.887, 0.962)

0.72

 > 10.86

81

91

SP-A1

0.893 (0.841, 0.932)

0.64

 ≤ 82.03

72

92

CBI

0.992 (0.967, 0.999)

0.93

 > 0.87

97

96

KC versus control

Max inverse radius

0.923 (0.878, 0.956)

0.71

 > 0.19

95

76

DA ratio max (2 mm)

0.953 (0.913, 0.978)

0.77

 > 5.13

83

94

Pachy slope

0.919 (0.873, 0.953)

0.69

 > 48.46

87

82

DA ratio max (1 mm)

0.914 (0.866, 0.949)

0.71

 > 1.66

86

85

ARTh

0.992 (0.967, 0.999)

0.96

 ≤ 364.89

97

99

Integrated radius

0.965 (0.929, 0.986)

0.79

 > 10.50

86

93

SP-A1

0.973 (0.939, 0.991)

0.84

 ≤ 91.64

87

97

CBI

0.999 (0.980, 1.000)

0.99

 > 0.50

99

100

  1. SKC Subclinical keratoconus, KC Keratoconus, DA Deformation amplitude, ARTh Ambrósio’s relational thickness horizontal, bIOP Biomechanical corrected intraocular pressure, SP-A1 Stiffness parameter at the first applanation, CBI Corvis biomechanical index.