Table 1 Prediction targets of fucosterol.

From: Exploration in the mechanism of fucosterol for the treatment of non-small cell lung cancer based on network pharmacology and molecular docking

Pharma model

Gene symbol

z-score

3f0r

HDAC8

2.82743

1qyx

HSD17B1

2.70536

1o6u

SEC14L2

2.68742

1n83

RORA

2.39228

1a28

PGR

2.2175

1ya3

NR3C2

2.13319

1s9j

MAP2K1

2.12046

1q22

SULT2B1

1.98504

1pic

PIK3R1

1.88125

1lv2

HNF4G

1.83771

1rhr

CASP3

1.80882

1osh

NR1H4

1.79715

830c

MMP13

1.78365

1rbp

RBP4

1.71609

1lho

SHBG

1.70322

1mrq

AKR1C1

1.70301

1sz7

TRAPPC3

1.6669

3czr

HSD11B1

1.65102

2piw

AR

1.6069

1fd0

RARG

1.59522

1d4p

F2

1.55496

1gse

GSTA1

1.54788

1uhl

NR1H3

1.52908

1hrk

FECH

1.52472

2iiv

DPP4

1.50916

1s0z

VDR

1.49636

1dkf

RARA

1.49513

2i6b

ADK

1.38413

1o1v

FABP6

1.35079

1ydt

PRKACA

1.31178

2shp

PTPN11

1.28799

2fjm

PTPN1

1.27676

2j14

PPARD

1.27187

1 × 0n

GRB2

1.2585

3bbt

ERBB4

1.25573

1l8j

PROCR

1.23987

2vx0

EPHB4

1.23974

1he3

BLVRB

1.19363

1pq2

CYP2C8

1.19205

1j99

SULT2A1

1.08311

1cbs

CRABP2

1.06101

1sm2

ITK

1.04514

1upw

NR1H2

1.03078

1qpd

LCK

1.00159

1uym

HSP90AB1

0.997933

1hov

MMP2

0.978531

1h9u

RXRB

0.976261

1u59

ZAP70

0.97084

1fe3

FABP7

0.963876

19gs

GSTP1

0.95545

2hzi

ABL1

0.954306

1yvj

JAK3

0.922657

1m48

IL2

0.917557

1t84

WAS

0.909365

1dxo

NQO1

0.886825

1j78

GC

0.867991

2p4i

TEK

0.803103

1iz2

SERPINA1

0.79593

1oiz

TTPA

0.795317

1ln3

PCTP

0.794336

1t4e

MDM2

0.78729

1xap

RARB

0.775562

1qkt

ESR1

0.767258

1r9o

CYP2C9

0.742597

1qip

GLO1

0.733894

1hmt

FABP3

0.731703

1bl6

MAPK14

0.730803

2rfn

MET

0.721237

1i7g

PPARA

0.707586

1pmn

MAPK10

0.678619

1e7a

ALB

0.644744

2oi0

ADAM17

0.634049

1cg6

MTAP

0.623444

1ma0

ADH5

0.608206

1g3m

SULT1E1

0.594411

1xjd

PRKCQ

0.557908

2uwd

HSP90AA1

0.555214

1oj9

MAOB

0.540688

1njs

GART

0.529254

1xvp

NR1I3

0.502645

2pjl

ESRRA

0.488399

1nhz

NR3C1

0.486782

1j96

AKR1C2

0.454473

2ipw

AKR1B1

0.434142

1p49

STS

0.426598

1xbb

SYK

0.421996

1okl

CA2

0.418201

2qu2

BACE1

0.398063

1ih0

TNNC1

0.394868

1sa4

FNTA

0.387846

1l6l

APOA2

0.385162

2fgi

FGFR1

0.36325

2pe0

PDPK1

0.355588

2h8h

SRC

0.34725

2itp

EGFR

0.342717

1xor

PDE4D

0.333997

1jqe

HNMT

0.312737

1shj

CASP7

0.309471

2iku

REN

0.285831

2pg2

KIF11

0.27567

3bgp

PIM1

0.259029

2ywp

CHEK1

0.245709

1t46

KIT

0.241973

1s95

PPP5C

0.227167

1itu

DPEP1

0.226319

2b53

CDK2

0.222033

2jbp

MAPKAPK2

0.216487

3cjg

KDR

0.212231

1n7i

PNMT

0.205326

1egc

ACADM

0.198463

1so2

PDE3B

0.191704

1l9n

TGM3

0.19101

2bxr

MAOA

0.187567

1hw8

HMGCR

0.158181

1tt6

TTR

0.155605

2o9i

NR1I2

0.148658

1 × 89

LCN2

0.147746

1j4i

FKBP1A

0.145396

1xlz

PDE4B

0.141599

1s8c

HMOX1

0.137498

1tjj

GM2A

0.121157

1mx1

CES1

0.0987688

2g01

MAPK8

0.0924675

1reu

BMP2

0.0907675

1fzv

PGF

0.0881642

1s1p

AKR1C3

0.0878495

1r7y

ABO

0.0714749

1pme

MAPK1

0.0689871

1g4k

MMP3

0.0676583

1h6g

CTNNA1

0.0673048

1vj5

EPHX2

0.0595376

2nn7

CA1

0.049744

2pin

THRB

0.0116825

1gzr

IGF1

0.00629983

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