Table 2 Differences in COX2 and PGE2 concentration compared to baseline and between condition interactions.
From: The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
n = 9 | Hot | TN | Cold | Hot vs TN | Hot vs cold | TN vs cold | |
|---|---|---|---|---|---|---|---|
COX2 (ng/ml) | |||||||
BL | 31.07 (20.44 to 45.66) | 38.27 (27.99 to 68.66) | 37.22 (28.15 to 49.27) | P value | 0.2573 | 0.0571 | 0.4308 |
ES | 0.55□ | 0.78▲ | 0.08■ | ||||
CI (95%) | − 14.86 to 0.45 | − 14.04 to 1.74 | − 6.84 to 8.94 | ||||
60 | − 0.53 (− 51.8 to 6.80) | − 7.45 (− 19.11 to − 0.71) | − 2.87 (− 12.82 to 8.02) | P value | 0.0036 | 0.312 | 0.0502 |
ES | 1.35● | 0.42□ | 0.38□ | ||||
CI (95%) | 2.34 to 11.50 | − 2.24 to 6.92 | − 9.16 to 0.0 | ||||
120 | 0.58 (− 7.59 to 9.80) | − 8.55 (− 23.65 to − 2.08) | − 7.00 (− 16.52 to 3.65) | P value | 0.0002 | 0.0015 | 0.5001 |
ES | 1.36● | 1.12● | 0.22□ | ||||
CI (95%) | 4.54 to 13.71 | 2.99–12.16 | − 6.14 to 3.03 | ||||
PGE2 (pg/ml) | |||||||
BL | 9.63 (8.44 to 10.46) | 9.00 (8.02 to 9.82) | 8.54 (7.29 to 10.02) | P value | 0.0736 | 0.0031 | 0.1962 |
ES | 0.86▲ | 1.15▲ | 0.48□ | ||||
CI (95%) | − 0.62 to 1.32 | 0.383–1.81 | − 0.25 to 1.18 | ||||
60 | − 0.02 (− 0.86 to 0.95) | 0.21 (− 0.27 to 0.97) | 0.31 (− 0.94 to 1.44) | P value | 0.3075 | 0.1528 | 0.6777 |
ES | 0.48□ | 0.51□ | 0.16■ | ||||
CI (95%) | − 0.68 to 0.22 | − 0.77 to 0.12 | − 0.54 to 0.35 | ||||
120 | − 0.6 (− 1.92 to 0.08) | 0.18 (− 0.36 to 0.65) | 0.20 (− 0.82 to 1.25) | P value | 0.0005 | 0.0003 | 0.9307 |
ES | 1.54● | 1.12● | 0.03■ | ||||
CI (95%) | − 1.27 to − 0.38 | − 1.29 to − 0.4 | − 0.47 to 0.43 | ||||
