Table 3 Results from random coefficient model analysis.
From: The influence of environmental and core temperature on cyclooxygenase and PGE2 in healthy humans
COX2/Tc (n = 8) | PGE2/Tc (n = 8) | COX2/PGE2 (n = 9) | ||||
|---|---|---|---|---|---|---|
Random coefficient | Time | Random coefficient | Time | Random coefficient | Time | |
All conditions | ||||||
P value | 0.1585 | < 0.0001 | 0.0730 | < 0.0001 | 0.3437 | 0.2838 |
T value | 1.492 | 6.807 | 2.009 | 9.479 | 0.971 | 1.10 |
Estimate | 0.003 | 0.12 | 0.38 | 0.14 | 0.01 | 0.096 |
CI (95%) | − 0.002 to 0.009 | 0.08 to 0.15 | − 0.004 to 0.08 | − 0.11 to 0.17 | − 0.01 to 0.03 | − 0.09 to 0.28 |
COLD vs. TN | ||||||
P value | 0.0749 | 0.9985 | 0.0079 | 0.0300 | 0.0243 | 0.9468 |
T value | 1.906 | 0.002 | 3.03 | 2.331 | 2.388 | − 0.067 |
Estimate | 0.008 | 0.00004 | 0.122 | 0.09 | 0.03 | − 0.007 |
CI (95%) | − 0.0009 to 0.17 | − 0.04 to 0.04 | 0.37 to 0.21 | 0.009 to 0.17 | 0.003 to 0.05 | − 0.23 to 0.21 |
COLD | ||||||
P value | 0.5917 | 0.0378 | 0.0631 | 0.0372 | 0.0012 | 0.1359 |
T value | − 0.550 | − 2.313 | 2.04 | − 2.338 | 8.383 | 1.606 |
Estimate | − 0.004 | − 0.20 | 0.098 | − 0.17 | 0.10 | 0.29 |
CI (95%) | − 0.017 to 0.01 | − 0.39 to − 0.01 | − 0.006 to 0.20 | − 0.33 to − 0.01 | 0.05 to 0.14 | − 0.11 to 0.68 |
TN | ||||||
P value | 0.5935 | 0.8256 | 0.0202 | 0.8901 | 0.1625 | 0.9620 |
T value | 0.547 | 0.228 | 3.111 | 0.144 | 1.469 | − 0.048 |
Estimate | 0.005 | 0.007 | 0.17 | 0.004 | 0.21 | − 0.008 |
CI (95%) | − 0.16 to 0.03 | − 0.06 to 0.08 | 0.04 to 0.30 | − 0.06 to 0.07 | − 0.01 to 0.05 | − 0.36 to 0.35 |
HOT | ||||||
P value | 0.0986 | 0.0985 | 0.1506 | 0.0709 | 0.0619 | 0.0077 |
T value | − 1.861 | 1.936 | 1.560 | 2.021 | − 2.039 | − 3.580 |
Estimate | − 0.01 | 0.095 | 0.10 | 0.14 | − 0.047 | − 0.57 |
CI (95%) | − 0.31 to 0.003 | − 0.02 to 0.21 | − 0.44 to 0.25 | − 0.01 to 0.30 | − 0.09 to 0.003 | − 094 to − 0.20 |
