Figure 8 | Scientific Reports

Figure 8

From: In vitro and in vivo inhibition of malaria parasite infection by monoclonal antibodies against Plasmodium falciparum circumsporozoite protein (CSP)

Figure 8

MAb reactivity to sporozoite. (A) ELISA curves of mAbs binding to transgenic P. berghei sporozoites carrying the P. falciparum CSP gene. (B) Mean ng/ml that resulted in OD = 1 for the sporozoite ELISA. Data from two independent experiments are shown as symbols. (C) Representative CSP reaction assay at 100 ng/ml mAb, performed twice using live transgenic P. berghei sporozoites carrying a functional P. falciparum CSP gene. Arrows indicate a typical tail-like CSP reaction at the ends of sporozoites.

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