Figure 3 | Scientific Reports

Figure 3

From: Exploratory classification of clinical phenotypes in Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis using cluster analysis

Figure 3

Classification tree analysis of 427 patients with antineutrophil cytoplasmic antibody-associated vasculitis in model 2. The dominant clinical feature (over 75%) is used to name each class. The observed number of individuals allocated to each class is shown in each column. The algorithm was initiated on the basis of MPO-ANCA positivity and was subsequently allocated by s-Cr and CRP levels. Among 47 patients with MPO-ANCA negativity, 39 were assigned to Cluster 1. Among 178 MPO-ANCA-positive patients without s-Cr elevation, 133 were assigned to Cluster 3. Among 65 MPO-ANCA-positive patients with s-Cr elevation and high CRP, 54 were assigned to Cluster 3. Among the remining 137 patients with s-Cr elevation and without high CRP, 117 were assigned to Cluster 4. The overall concordance rate was 80%. CRP C-reactive protein, MPO-ANCA myeloperoxidase-antineutrophil cytoplasmic antibody, s-Cr serum creatinine.

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