Table 2 Comparison of patient characteristics across four clusters based on model 2.
Cluster 1 MPO-ANCA (−) (n = 42) | Cluster 2 Renal with high CRP (n = 71) | Cluster 3 Non-renal (n = 157) | Cluster 4 Renal without high CRP (n = 157) | |
|---|---|---|---|---|
Female/male | 22/20 | 32/39 | 96/61 | 93/64 |
Ages (years) | 63 (59–73) | 73 (65–79) | 73 (64–78) | 73 (64–78) |
GPA (%) | 34 (81) | 19 (27) | 23 (15) | 10 (6) |
MPA (%) | 5 (12) | 49 (69) | 84 (53) | 132 (84) |
Unclassifiable (%) | 3 (7) | 3 (4) | 50 (32) | 15 (10) |
MPO + ANCA (%) | 3 (7) | 71 (100) | 150 (96) | 156 (99) |
PR3-ANCA (%) | 33 (79) | 6 (9) | 5 (3) | 3 (2) |
Serum creatinine (mg/dL) | 0.8 (0.6–1.4) | 2.9 (1.6–4.6) | 0.76 (0.62–1.0) | 2.4 (1.3–4.5) |
< 1.3 (%) | 30 (71) | 8 (11) | 140 (89) | 38 (24) |
≥ 1.3, < 5.5 (%) | 11 (26) | 47 (66) | 17 (11) | 92 (59) |
≥ 5.5 (%) | 1 (2) | 16 (23) | 0 | 27 (17) |
CRP (mg/dL) | 3.9 (1–11) | 13 (11–17) | 9.6 (6.1–13) | 1.6 (0.2–5.1) |
< 2.6 (%) | 14 (33) | 0 | 7 (4) | 99 (63) |
≥ 2.6, ≤ 10 (%) | 15 (36) | 10 (14) | 74 (47) | 56 (36) |
> 10 (%) | 13 (31) | 61 (86) | 76 (48) | 2 (1) |
ILD (%) | 6 (14) | 31 (44) | 86 (55) | 62 (39) |
General (%) | 26 (62) | 60 (85) | 140 (89) | 58 (37) |
Cutaneous (%) | 5 (12) | 12 (17) | 32 (20) | 10 (6) |
Mucous membranes/eyes (%) | 18 (43) | 8 (11) | 19 (12) | 5 (3) |
Ear nose and throat (%) | 34 (81) | 23 (32) | 19 (12) | 13 (8) |
Chest (%) | 18 (43) | 49 (69) | 56 (36) | 49 (31) |
Cardiovascular (%) | 3 (7) | 14 (20) | 3 (2) | 14 (9) |
Abdominal (%) | 1 (2) | 2 (3) | 1 (1) | 0 |
Renal (%) | 24 (57) | 71 (100) | 105 (67) | 148 (94) |
Nervous system (%) | 13 (31) | 27 (38) | 85 (54) | 11 (7) |
