Figure 2 | Scientific Reports

Figure 2

From: Single-cell differential splicing analysis reveals high heterogeneity of liver tumor-infiltrating T cells

Figure 2

Differential usage of junctions in the UTR regions across T cell clusters. (A) Frequency of DESJ in the UTR regions is significantly higher than in the coding regions. These points represent T cell clusters. (B) Length difference between DESJ and non-DESJ in the coding region and the UTR region. (C) A bar plot depicting the fraction of DEG genes among DAS genes across CD8+ T cells. (D) Sashimi plots illustrating the read distribution of ARHGAP9 in CD8+ T cells from P0508. The colors represent different isoforms. This alternative splicing of ARHGAP9 happens in the 5′ UTR regions. Naïve T cells (C01_CD8.LEF1) show obvious differential usage of isoforms compared to other clusters. (E) Results of KEGG pathway analysis of genes with differential splicing in the UTR regions.

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