Table 2 Univariate analysis of clinicopathological characteristics and incidence of distant metastasis.

From: Risk factors for distant metastasis in locoregionally controlled oral squamous cell carcinoma: a retrospective study

Variables

Incidence of distant metastasis (%)

p value

Sex

 

0.081

Male

27/573 (5.1)

Female

9/354 (2.5)

Primary site

 

0.003*

PIOC of the mandible

4/16 (25.0)

Others

32/871 (3.7)

Histological differentiation

 

< 0.001*

Well/Moderately

26/824 (3.2)

Poorly

10/63 (15.9)

Initial treatment for primary tumor

 

0.202

Surgery

29/775 (3.7)

Brachytherapy

7/112 (6.3)

pN

 

< 0.001*

No

5/642 (0.8)

Yes

31/245 (12.7)

Number of metastatic nodes

 

< 0.001*

0–3

18/821 (2.2)

≥ 4

18/66 (27.3)

Level of metastatic node

 

< 0.001*

No metastasis or I + II + III

27/869 (3.1)

IV + V

9/18 (50.0)

Contralateral node metastasis

 

< 0.001*

No

27/850 (3.2)

Yes

10/38 (26.3)

ENE

 

< 0.001*

No

11/748 (1.5)

Yes

25/139 (18.0)

Postoperative CT and/or RT

 

< 0.001*

No

7/732 (1.0)

Yes

29/155 (18.7)

Total

36/887 (4.1)

 
  1. PIOC, primary intraosseous carcinoma; CT, chemotherapy; RT, radiotherapy; ENE, extranodal extension.
  2. *Significant at p < 0.05.