Table 3 Agreement between gestalt and component by view scores.

From: Key factors in a rigorous longitudinal image-based assessment of retinopathy of prematurity

Component by view

% Agreement

Absolute agreement (95% CI)

Cohen’s weighted kappa (95% CI)

A. Individual scoresa

Vascular tortuosity

 CVT

81.6

0.56 (0.49–0.63)

0.57 (0.50–0.65)

 IVT

74.9

0.42 (0.34–0.50)

0.43 (0.35–0.51)

 NVT

77.4

0.40 (0.32–0.48)

0.44 (0.35–0.53)

 SVT

75.4

0.39 (0.31–0.47)

0.42 (0.33–0.51)

 TVT

78.8

0.45 (0.38–0.53)

0.48 (0.39–0.56)

Vascular dilation

 CVD

65.1

0.22 (0.13–0.31)

0.21 (0.13–0.29)

 IVD

62.9

0.21 (0.12–0.30)

0.19 (0.11–0.27)

 NVD

62.1

0.12 (0.02–0.21)

0.13 (0.05–0.21)

 SVD

59.7

0.39 (0.31–0.47)

0.12 (0.04–0.19)

 TVD

63.3

0.45 (0.38–0.53)

0.15 (0.07–0.23)

Stage

 CST

25.4

0.002 (− 0.04 to 0.05)

0.003 (− 0.002 to 0.009)

 IST

41.6

0.14 (− 0.012 to 0.28)

0.14 (0.10–0.18)

 NST

50.2

0.31 (0.04–0.35)

0.22 (0.17–0.27)

 SST

33.9

0.06 (− 0.03 to 0.16)

0.07 (0.04–0.09)

 TST

59.0

0.3 (0.11–0.45)

0.32 (0.26–0.38)

Heme

 CH

25.1

0.002 (− 0.04 to 0.05)

0.002 (− 0.002 to 0.01)

 IH

25.6

0.002 (− 0.04 to 0.05)

0.005 (− 0.001 to 0.01)

 NH

27.9

0.02 (− 0.03 to 0.08)

0.02 (0.009–0.4)

 SH

24.9

0.004 (− 0.04 to 0.05)

− 0.004 (− 0.02 to 0.01)

 TH

27.1

0.02 (− 0.03 to 0.08)

0.01 (− 0.004 to 0.03)

Growth of vessels

 CG

25.4

− 0.003 (− 0.04 to 0.04)

0.01 (− 0.007 to 0.03)

 IG

25.6

− 0.04 (− 0.11 to 0.04)

0.006 (− 0.01 to 0.02)

 NG

26.0

− 0.02 (− 0.06 to 0.04)

0.02 (− 0.008 to 0.04)

 SG

26.7

− 0.02 (− 0.06 to 0.04)

0.02 (− 0.005 to 0.04)

 TH

26.2

− 0.01 (− 0.06 to 0.04)

0.01 (− 0.006 to 0.04)

B. Longitudinal scoresb

Vascular tortuosity

 CVT

42.9

0.82 (0.73–0.88)

0.61 (0.52–0.70)

 IVT

42.9

0.68 (0.55–0.78)

0.51 (0.39–0.63)

 NVT

39.3

0.68 (0.55–0.78)

0.48 (0.37–0.59)

 SVT

36.9

0.66 (0.52–0.77)

0.47 (0.35–0.59)

 TVT

42.9

0.66 (0.52–0.77)

0.48 (0.35–0.60)

Vascular dilation

 CVD

22.6

0.26 (0.05–0.44)

0.17 (0.04–0.30)

 IVD

20.2

0.32 (0.11–0.49)

0.21 (0.08–0.34)

 NVD

23.8

0.18 (− 0.034 to 0.38)

0.14 (− 0.009 to 0.28)

 SVD

19.0

0.66 (0.52–0.77)

0.13 (− 0.005 to 0.26)

 TVD

22.6

0.66 (0.52–0.77)

0.16 (0.02–0.30)

Stage

 CST

14.3

0.003 (− 0.05 to 0.08)

0.001 (− 0.001 to 0.004)

 IST

17.9

0.2 (− 0.08 to 0.46)

0.13 (0.07–0.20)

 NST

23.8

0.3 (− 0.07 to 0.57)

0.22 (0.13–0.31)

 SST

14.3

0.08 (− 0.06–0.26)

0.05 (0.02–0.08)

 TST

21.4

0.38 (− 0.07–0.67)

0.25 (0.17–0.34)

Heme

 CH

14.3

0.003 (− 0.05 to 0.08)

0.001 (− 0.001 to 0.004)

 IH

14.3

0.003 (− 0.05 to 0.08)

0.001 (− 0.001 to 0.004)

 NH

15.5

0.03 (− 0.05 to 0.12)

0.02 (− 0.006 to 0.04)

 SH

14.3

0.004 (− 0.05 to 0.08)

0.003 (− 0.001 to 0.007)

 TH

14.3

0.03 (− 0.05 to 0.12)

0.02 (− 0.006 to 0.03)

Growth of vessels

 CG

16.7

− 0.003 (− 0.05 to 0.07)

0.01 (− 0.003 to 0.03)

 IG

17.9

− 0.04 (− 0.12 to 0.08)

0.01 (− 0.004 to 0.02)

 NG

16.7

− 0.03 (− 0.09 to 0.06)

0.01 (− 0.004 to 0.03)

 SG

16.7

− 0.03 (− 0.09 to 0.06)

0.01 (− 0.003 to 0.03)

 TH

19.0

− 0.02 (− 0.08 to 0.06)

0.02 (0.001 to 0.03)

  1. Central, inferior, nasal, superior, and temporal vascular tortuosity (CVT, IVT, NVT, SVT, TVT); central, inferior, nasal, superior, and temporal vascular dilation (CVD, IVD, NVD, SVD, TVD); central, inferior, nasal, superior, and temporal stage (CST, IST, NST, SST, TST); central, inferior, nasal, superior, and temporal heme (CH, IH, NH, SH, TH); and central, inferior, nasal, superior, and temporal growth of vessels (CG, IG, NG, SG, TG).
  2. aIndividual scores consist of evaluation of a single week’s as compared to the prior week.
  3. bLongitudinal scores consist of the sum of gestalt or view scores for each eye across all weeks.