Figure 11 | Scientific Reports

Figure 11

From: Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N′-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage

Figure 11

I Pharmacophore model of MMINA compound. (A) 3D representation of MMINA pharmacophore model. Red spheres repersents hydrogen bond acceptor (HBA), green spheres showing hydrogen bond donor (HBD) and yellow spheres depicting aromatic rings. (B) The same color theme with same descriptors are represented in 2D conformation. II: The RMSF plot of all the system trajectories. (A) COX2 (B) GPX, (C) IL1 (D) SOD, (E) STAT3, (F) iNOS, (G) NFKB, (H) p65 and (I) TNF-α.

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