Figure 8 | Scientific Reports

Figure 8

From: Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N′-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage

Figure 8

Binding analysis of MMINA with COX2, STAT3, TNF-α, NF-κB and p65protein. In the 3D confirmation, protein is shown in snake ribbon while the MMINA is shown in grey ball and stick model. In 2D representation blue ball and stick model represent the MMINA, residues involved in hydrophobic interactions are shown in pink disc while the residues involved in covalent and coordinate covalent interactions are shown in green discs. orange lines indicating pi-interactions in p65.

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