Figure 5 | Scientific Reports

Figure 5

From: Specific detection of Staphylococcus aureus infection and marker for Alzheimer disease by surface enhanced Raman spectroscopy using silver and gold nanoparticle-coated magnetic polystyrene beads

Figure 5

(A) Surface enhanced Raman (SER) spectrum of streptavidin coated polystyrene particles covered by thorny Au particles (Strep@PS-tAuNPs), (B) SER spectrum of Strep@PS-tAuNPs after the addition of biotinylated antibody to Protein A (antiP@Strep@mPS-tAuNPs, (C) SER spectrum of antiP@Strep@mPS-tAuNPs after the addition of Protein A, (D) SER spectrum of Protein A@antiP@Strep@mPS-tAuNPs after the addition of real sterile joint knee fluid sample obtained by puncture from patients with osteoarthritis spiked subsequently by Staphylococcus aureus (STAU/JKF@antiP@Strep@mPS-tAuNPs). Laser excitation wavelength was 785 nm.

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