Figure 2

Sequence alignments of three VPs (VP1, VP2 and VP3) of EV-A71, CV-A16 and CV-A10. ESPript representation of structure-based sequence alignments of EV-A71 (GenBank accession no: EU703812), CV-A16 (GenBank accession no: JQ354992) and CV-A10 (GenBank accession no: KP009574) are shown. The second structure elements (β-sheets and α-helices) are shown above the corresponding alignment as arrows (β-sheets) and spirals (α-helices), respectively. The predicted epitopes are shown as black circles (core epitopes) and triangles (surrounding epitopes). The predicted results of CV-A10 are from our previous work. The alignments are colored according to the sequence identity among EV-A71, CV-A16 and CV-A10, on a scale of white (no identity) to red (full identity).