Figure 1 | Scientific Reports

Figure 1

From: Association of maternal gut microbiota and plasma metabolism with congenital heart disease in offspring: a multi-omic analysis

Figure 1

Comparisons of gut microbial alpha-diversity and beta-diversity between mothers of infants with CHD and mothers of infants without CHD. Compared with the controls, gut microbial diversity, as estimated by the Shannon index (a), Chao1 index (b), and the observed species (c), was significantly decreased in mothers of infants with CHD (all p < 0.05). (d) PCoA based on unweighted UniFrac distance showed that the overall gut microbiota composition was different between mothers of infants with CHD and controls (R2 = 0.144, p = 0.001). CHD congenital heart disease, PCoA principal coordinates analysis.

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