Table 1 List of protein differentially regulated in CTEPH patients versus controls.
Protein Accession numbers | Protein names | Gene names | log2 (ratio) |
|---|---|---|---|
O00469 | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 | PLOD2 | 2.47 |
Q5U0D2 | Transgelin | TAGLN | 2.41 |
A0A0P1J1R0 | Translationally-controlled tumor protein | TPT1 | 2.38 |
P68133 | Actin, alpha skeletal muscle; | ACTA1 | 2.23 |
V9HW83 | Retinal dehydrogenase 1 | HEL-S-53e | 1.71 |
H0YNW5 | Deoxyuridine 5-triphosphate nucleotidohydrolase, mitochondrial | DUT | 1.40 |
J3QR09 | Ribosomal protein L19; | RPL19 | 1.38 |
Q5ISS1 | ADP-ribosylation factor 1; | ARF1 | 1.34 |
P68366 | Tubulin alpha-4A chain | TUBA4A | 1.18 |
Q9UJC5 | SH3 domain-binding glutamic acid-rich-like protein 2 | SH3BGRL2 | 1.17 |
A0A024R222 | Phosphoserine aminotransferase | PSAT1 | 1.16 |
B4DDF4 | Calponin; | CNN2 | 1.13 |
B1AHB1 | DNA helicase;DNA replication licensing factor MCM5 | MCM5 | 1.11 |
B3KXZ4 | DNA helicase;DNA replication licensing factor MCM2 | MCM2 | 1.08 |
Q14566 | DNA replication licensing factor MCM6 | MCM6 | 1.05 |
Q8WX93 | Palladin | PALLD | 1.05 |
O95433 | Activator of 90 kDa heat shock protein ATPase homolog 1 | AHSA1 | 1.05 |
K7ELC2 | 40S ribosomal protein S15 | RPS15 | 1.02 |
Q8NG19 | Collagen alpha-1(XVIII) chain;Endostatin | COL18A1 | -1.00 |
L7UUZ7 | Integrin beta | ITGB3 | -1.01 |
A0A0S2Z3L0 | Electron transfer flavoprotein subunit alpha, mitochondrial | ETFA | -1.01 |
Q53YE7 | Amine oxidase [flavin-containing] A | MAOA | -1.02 |
B3KNK4 | Phosphatidate cytidylyltransferase | CDS2 | -1.03 |
Q8WYJ5 | Histidine triad nucleotide-binding protein 2, mitochondrial | HINT2 | -1.03 |
B4E2S7 | Lysosome-associated membrane glycoprotein 2 | LAMP2 | -1.04 |
A0A024R8T3 | Acyl-coenzyme A oxidase; | ACOX1 | -1.04 |
B4DEH0 | 39S ribosomal protein L10, mitochondrial | MRPL10 | -1.05 |
A0A0S2Z5A5 | Septin-9 | 43,352 | -1.05 |
Q96N83 | Podocalyxin | PODXL | -1.06 |
B4DKM6 | Serum paraoxonase/arylesterase 2 | PON2 | -1.06 |
A0A024RC61 | Aminopeptidase N | ANPEP | -1.07 |
P38117 | Electron transfer flavoprotein subunit beta | ETFB | -1.07 |
A0A096LPI6 | ES1 protein homolog, mitochondrial | C21orf33 | -1.09 |
Q6DHZ2 | cAMP-dependent protein kinase type II-beta regulatory subunit | PRKAR2B | -1.09 |
A0A024R9D7 | 2,4-dienoyl-CoA reductase, mitochondrial | DECR1 | -1.09 |
P49006 | MARCKS-related protein | MARCKSL1 | -1.10 |
Q53FJ5 | Prosaposin | PSAP | -1.10 |
B4E324 | Carboxypeptidase; | CTSA | -1.10 |
Q9NV96 | Cell cycle control protein 50A | TMEM30A | -1.10 |
Q14XT3 | Cytochrome c oxidase subunit 2 | COX2 | -1.11 |
P35580 | Myosin-10 | MYH10 | -1.11 |
B7Z8A2 | Prenylcysteine oxidase 1 | PCYOX1 | -1.11 |
Q96CM8 | Acyl-CoA synthetase family member 2, mitochondrial | ACSF2 | -1.12 |
Q9Y4D7 | Plexin-D1 | PLXND1 | -1.15 |
A0A024RAB6 | Basement membrane-specific heparan sulfate proteoglycan core protein;Endorepellin;LG3 peptide | HSPG2 | -1.16 |
B2R7D2 | Multiple inositol polyphosphate phosphatase 1 | MINPP1 | -1.16 |
A0A1B0GW44 | Cathepsin D; | HEL-S-130P | -1.17 |
A0A024RAD8 | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | ALDH4A1 | -1.17 |
P16284 | Platelet endothelial cell adhesion molecule | PECAM1 | -1.18 |
Q9UHL4 | Dipeptidyl peptidase 2 | DPP7 | -1.18 |
Q8TDB4 | Protein MGARP | MGARP | -1.19 |
P51970 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 | NDUFA8 | -1.21 |
Q9BVJ8 | Beta-hexosaminidase;Beta-hexosaminidase subunit alpha | HEXA | -1.21 |
B4DJQ8 | Dipeptidyl peptidase 1; | CTSC | -1.23 |
A8K9J6 | CD276 antigen | CD276 | -1.23 |
Q53FB6 | Aldehyde dehydrogenase, mitochondrial | ALDH2 | -1.25 |
O75923 | Dysferlin | DYSF | -1.25 |
P04275 | von Willebrand factor;von Willebrand antigen 2 | VWF | -1.26 |
P49407 | Beta-arrestin-1 | ARRB1 | -1.27 |
Q9Y2Q5 | Ragulator complex protein LAMTOR2 | LAMTOR2 | -1.28 |
Q6IB89 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 | NDUFA7 | -1.29 |
Q9NSC5 | Homer protein homolog 3 | HOMER3 | -1.31 |
Q53H18 | Beta-galactosidase | GLB1 | -1.32 |
A0A0C4DFN8 | NADPH:adrenodoxin oxidoreductase, mitochondrial | FDXR | -1.34 |
A8K335 | Gamma-glutamyl hydrolase | GGH | -1.34 |
A0A140VJL0 | 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial | HIBCH | -1.35 |
A0A024R8Q1 | Lysosomal alpha-glucosidase; | GAA | -1.36 |
B3KQQ0 | Peptidyl-prolyl cis–trans isomerase FKBP9 | FKBP9 | -1.39 |
A0A090N7X0 | GTPase IMAP family member 4 | HIMAP4 | -1.39 |
Q5URX0 | Beta-hexosaminidase; | HEXB | -1.41 |
P36551 | Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | CPOX | -1.41 |
A0A024RA75 | 3-hydroxyisobutyrate dehydrogenase | HIBADH | -1.42 |
B4DTT0 | N-acetylglucosamine-6-sulfatase | DKFZp686E12166 | -1.44 |
A0A090N8H2 | GTPase IMAP family member 8 | hIAN6 | -1.45 |
Q7Z7M4 | Superoxide dismutase; | SOD2 | -1.47 |
Q92626 | Peroxidasin homolog | PXDN | -1.48 |
Q14165 | Malectin | MLEC | -1.52 |
B4DSE2 | Tripeptidyl-peptidase 1 | TPP1 | -1.53 |
P04040 | Catalase | CAT | -1.55 |
Q96DI8 | Heme oxygenase 1 | HMOX1 | -1.55 |
B4DJI2 | Granulins; | GRN | -1.56 |
Q5TBU5 | Adipogenesis regulatory factor | hCG_1773630 | -1.58 |
P30837 | Aldehyde dehydrogenase X, mitochondrial | ALDH1B1 | -1.58 |
Q5NKV8 | Intercellular adhesion molecule 1 | ICAM1 | -1.59 |
A0A024R5L0 | Lysosomal Pro-X carboxypeptidase | PRCP | -1.91 |
Q8NHP8 | Putative phospholipase B-like 2; | PLBD2 | -2.01 |
A0A090N8Z4 | GTPase IMAP family member 1 | IMAP1 | -2.04 |
K7ERP4 | Glutathione peroxidase; | GPX4 | -2.18 |
A0A024RDG9 | 3-hydroxybutyrate dehydrogenase type 2 | BDH2 | -2.21 |
B2R769 | Endoplasmic reticulum aminopeptidase 2 | ERAP2 | -2.53 |
V9HW74 | Ubiquitin carboxyl-terminal hydrolase; | HEL-117 | -3.17 |
