Figure 3


Informant rated executive functions. (a) BRIEF-P results for children with DS younger than 8 years (n = 49) Normative data (n = 1747, age 2–5 years) from Gioia et al.17,18. b) Parent’s version of the BRIEF for children of 8 years and older with DS (n = 89). Normative data (n = 3333, age 5–17 years) from Huizinga et al.20,21. c) Teacher’s version of the BRIEF for children of 8 years and older with DS (n = 39). Normative data (n = 941, age 5–11 years) from Huizinga et al.20,21. Data of children with DS are typically above the norm indicating that children with DS scored poorer on this executive functions scale. Blue bullets: Measured boys with DS (BRIEF-P n = 27, BRIEF parents’ version n = 22, teachers’ version n = 18). Red bullets: Measured girls with DS (BRIEF-P n = 22, BRIEF parents’ version n = 28, teachers’ version n = 21). Green curve: Loess line fitted to the data from ratings on children with DS pooled across boys and girls. Blue curve: Norm scores (mean) of typically developing boys. Red curve: Norm scores (mean) of typically developing girls. Light blue dashed lines: upper and lower bound of the 95% confidence interval of norm scores of typically developing boys. Pink dashed lines: upper and lower bound of the 95% confidence interval of norm scores of typically developing girls.