Figure 4 | Scientific Reports

Figure 4

From: Burkholderia cenocepacia transcriptome during the early contacts with giant plasma membrane vesicles derived from live bronchial epithelial cells

Figure 4

Heat map of B. cenocepacia K56-2 genes expression during adhesion to 16HBE14o- GPMVs (A). Colors from white to pink indicate upregulated cellular genes; colors from white to blue indicate downregulated cellular genes. Data from three replicas are represented. Heat maps were created using Heatmapper online platform (http://www.heatmapper.ca)70. Dataset validation by qRT-PCR (B). Transcription levels of B. cenocepacia K56-2 BCAL0729, BCAL3098, BCAM2531, BCAM2418, BCAL1829, BCAL2933 and BCAM1570 genes were obtained by qRT-PCR from bacteria adherent to 16HBE14o- GPMVs (30 min of contact). Expression levels are represented as Log2(Fold change) relative values in comparison to the expression levels of non-adherent bacteria. All the results are from three independent experiments, bars indicate SD (**P < 0.01; ****P < 0.0001).

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