Figure 2
The steady-state concentrations of lactate, total choline (tCho) and total N-acetylaspartate (tNAA) concentrations at the day of HP glucose infusion. Localized 1H spectra were acquired in an 8 μL voxel, located in the cell injected hemisphere, as designated by the white square in the image (red spectra), corresponding voxel in the contralateral hemisphere (not shown) and in similar voxel in control animals (black spectra). The presented concentrations are only from the animals that received the HP 13C glucose bolus. In black are concentrations in the medium injected hemisphere in controls (control 1–3). In red, are concentrations in the tumor cell injected hemisphere (tumor 1–3), and in the blue concentrations in the contralateral hemisphere (contra 1–3) respectively, The number of ‘*’ represent statistically significant levels of p = 0.05, 0.01, 0.005, 0.001, 0.0005 and 0.00005. NCH numbers indicate the identification number of each individual mouse.
