Figure 4 | Scientific Reports

Figure 4

From: Repetitive transcranial magnetic stimulation restores altered functional connectivity of central poststroke pain model monkeys

Figure 4

Changes in resting-state functional connectivity obtained from ROI-to-ROI analysis. (a) Changes in functional connectivity between the baseline and after CPSP development and (b) between the CPSP and after rTMS treatment. The red and blue lines indicate increased and decreased functional connectivity, respectively. The graphical figures are made by Conn toolbox. (c) The values of the functional connectivity between the left amygdala and the left MD for the two monkeys are shown. *p < 0.005, **p < 0.00005 after Bonferroni correction. aINS agranular insular cortex, AMY amygdala, Cd caudate, CPSP central poststroke pain, dINS dysgranular insular cortex, FO frontal operculum, gINS granular insular cortex, HG Heshcel’s gyrus, Lt left, M1 motor cortex, MD mediodorsal nucleus of the thalamus, PO Parietal operculum cotex, PP planum polare, Pu putamen, ROI region of interest, Rt right, rTMS repetitive transcranial magnetic stimulation, S1 primary somatosensory cortex, S2 secondary somatosensory cortex, SMG supramarginal gyrus.

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