Figure 5

Detailed connectivity between the mediodorsal nucleus (MD) of the thalamus and amygdala obtained from seed-to-voxel analyses. Coronal (left), axial (centre), and sagittal (right) slices of the T2-weighted macaque atlas are shown. (a) Results of seed-to-voxel analysis when the MD is selected as the seed. The red lines indicate the edge of the voxel clusters in which the functional connectivity is significantly changed (voxel level uncorrected p < 0.001 and cluster level p-FDR < 0.05). The coloured areas indicate subregions of the amygdala drawn by using the template atlas. (b) Results of seed-to-voxel analysis when the amygdala is selected as the seed. We adjusted the significance level of the cluster size to detect focal changes (cluster size > 5). Coloured areas indicate the nucleus of the thalamus, drawn by using the template atlas. The xyz coordinate is defined at the anterior commissure. A anterior, CPSP central poststroke pain, L left.