Table 2 Uni- and multi-variate analysis of factors associated with hepatoma recurrence (n = 94).

From: Liver stiffness and insulin resistance in predicting recurrence for early stage hepatoma patients after curative resection

Associated factor

Comparison

Univariate

HR (95% CI)

p value

Multivariate*

HR (95% CI)

p value

Hepatitis etiology

NBC

Reference

   

B

2.86 (0.38–21.57)

0.308

  

C

4.73 (0.63–35.32)

0.129

  

BC

11.52 (1.18–112.03)

0.035

  

Hepatitis treatment

Yes

No

Reference

0.56 (0.28–1.13)

0.105

  

LS (kPa)

 

1.03 (1.01–1.05)

0.014

1.03 (1.01–1.05)

0.011

ICG (%)

 

1.04 (1.00–1.08)

0.053

  

AST (U/L)

 

1.01 (1.00–1.02)

0.087

  

ALP (U/L)

 

1.02 (1.00–1.03)

0.035

  

MELD

 

1.22 (0.94–1.58)

0.127

  

HOMA-IR

 

1.11 (1.00–1.23)

0.057

  
  1. B hepatitis B virus, C hepatitis C virus, NBNC non-hepatitis B virus and non-hepatitis C virus, LS liver stiffness, ICG indocyanine green, AST aspartate aminotransferase, ALP alkaline phosphatase, MELD model for end stage liver disease, HOMA-IR homeostatic model assessment for insulin resistance, *all characteristics in Table 1 were included in the univariable analysis and those with p values < 0.2 was entered into stepwise multivariable analysis.
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