Table 1 Standard enthalpy of reaction of glycolysis \(\Delta^{R} h^{0}\) and standard Gibbs energy of reaction of glycolysis \(\Delta^{R} g^{0}\) at pH 7 with the respective sources.

From: New thermodynamic activity-based approach allows predicting the feasibility of glycolysis

Reaction

\(\Delta^{R} h^{0}\)

\(\Delta^{R} g^{0}\)(298.15 K)

kJ mol−1

Source

kJ mol−1

Source

Hexokinase

− 23.8 ± 0.7

16

− 17.8 ± 0.5

17

G6P isomerase

12.1 ± 0.2

18

2.94 ± 0.05

18

PFK

− 9.5

19 + 20a

− 9.3 ± 0.3

13 + 19 + this workb

Aldolase

48.97

21

22 ± 2

14 + 21 + this workc

TPI

18 ± 7

22

7.1 ± 0.3

22

GAPDH

4.6 ± 0.1

23

51.5 ± 0.4

23

PGK

− 49 ± 9

24

− 17.8 ± 0.2

24

PGAM

2 ± 5

12

− 5.8

15 + this workd

Enolase

27 ± 10

12

− 2.8 ± 0.2

12

PK

− 9.3

25

− 28 ± 1

26

  1. aValue originally from Redman–Furey19; according to Goldberg et al.20 calorimetrically determined enthalpies (using different buffers at pH 9.0 and 298.15 K) were used to calculate \({\Delta }^{{\text{R}}} h^{0}\) = 9.5 kJ mol−1 with the change in the binding of \({\text{H}}^{ + }\) and enthalpies of ionization of the buffers.
  2. b–dSee text for more detail.
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