Figure 6

Effect of prediabetes and early phase type 2 diabetes on inflammatory markers involved in endothelial dysfunction. Average expression of (a) IL-1 receptor (IL-1R, 80 kDa) and (b) IL-6 receptor (IL-6R, 80 kDa) and the loading protein GAPDH (37 kDa) in aorta and pulmonary artery (PA) of control (n = 4–5), HF (n = 3–5) and HFHSu (n = 3–4) animals. Representative western blots for each protein studied are depicted above the respective graphs. Representative bands were cropped due to the sample order in the membrane. For complete membrane image see Supplementary data. Values are presented as scatter plots ± SD; One-way ANOVA with Dunnet’s comparison test. *p < 0.05 and **p < 0.01 versus control animals.