Table 3 The effect of surgery on overall survival and cancer-specific survival based on different subgroup variables.
Prognostic factor | Overall survival | Cancer-specific survival | ||||||
|---|---|---|---|---|---|---|---|---|
P value | HR | Lower 95% CI | Higher 95% CI | P value | HR | Lower 95% CI | Higher 95% CI | |
Gender | ||||||||
Male | 0.000 | 4.198 | 3.142 | 5.610 | 0.000 | 6.194 | 3.924 | 9.777 |
Female | 0.000 | 5.443 | 4.096 | 7.234 | 0.000 | 7.226 | 4.808 | 10.859 |
Age | ||||||||
75–79 | 0.000 | 4.231 | 2.970 | 6.029 | 0.000 | 5.279 | 3.111 | 8.956 |
80–84 | 0.000 | 5.326 | 3.718 | 7.630 | 0.000 | 9.641 | 5.461 | 17.021 |
85–102 | 0.000 | 4.494 | 3.178 | 6.356 | 0.000 | 6.259 | 3.700 | 10.590 |
Grade | ||||||||
1 | 0.000 | 9.844 | 6.391 | 15.163 | 0.000 | 15.357 | 7.883 | 29.918 |
2 | 0.000 | 4.879 | 3.728 | 6.385 | 0.000 | 6.143 | 4.108 | 9.186 |
3 | 0.005 | 1.954 | 1.225 | 3.116 | 0.003 | 2.850 | 1.414 | 5.745 |
Race | ||||||||
Caucasian | 0.000 | 4.975 | 3.983 | 6.212 | 0.000 | 6.553 | 4.681 | 9.175 |
Asian | 0.000 | 4.470 | 2.206 | 9.058 | 0.001 | 5.644 | 1.960 | 16.251 |
African American | 0.019 | 2.439 | 1.156 | 5.146 | 0.004 | 4.862 | 1.642 | 14.399 |
Stage | ||||||||
I–II | 0.000 | 6.569 | 4.719 | 9.144 | 0.000 | 18.902 | 10.801 | 33.080 |
III–IV | 0.000 | 2.420 | 1.859 | 3.151 | 0.000 | 2.529 | 1.754 | 3.646 |
T classification | ||||||||
T1 | 0.000 | 4.943 | 2.784 | 8.773 | 0.000 | 8.891 | 3.126 | 25.287 |
T2 | 0.000 | 3.744 | 2.741 | 5.116 | 0.000 | 6.425 | 3.965 | 10.410 |
T3 | 0.000 | 2.314 | 1.481 | 3.616 | 0.002 | 2.875 | 1.497 | 5.522 |
T4a | 0.040 | 1.768 | 1.027 | 3.043 | 0.330 | 1.453 | 0.685 | 3.084 |
T4b | 0.509 | 0.019 | 0.000 | 2359.993 | – | |||
N classification | ||||||||
N0 | 0.000 | 5.475 | 4.178 | 7.175 | 0.000 | 13.282 | 8.416 | 20.962 |
N1 | 0.000 | 3.059 | 1.883 | 4.967 | 0.010 | 2.453 | 1.244 | 4.836 |
N2a | 0.616 | 434.450 | 0.000 | > 1000 | – | |||
N2b | 0.007 | 1.961 | 1.199 | 3.209 | 0.098 | 1.698 | 0.907 | 3.178 |
N2c | 0.173 | 2.190 | 0.709 | 6.768 | 0.120 | 3.636 | 0.715 | 18.487 |
N3 | 0.343 | 105.281 | 0.007 | 1,593,878.432 | 0.393 | 58.761 | 0.005 | 671,565.640 |
Tumor location | ||||||||
Dorsal surface of tongue | 0.007 | 3.960 | 1.456 | 10.772 | 0.121 | 6.936 | 0.599 | 80.262 |
Border of tongue | 0.000 | 6.838 | 3.947 | 11.844 | 0.000 | 9.806 | 4.518 | 21.284 |
Ventral surface of tongue | 0.000 | 4.307 | 2.164 | 8.571 | 0.000 | 9.476 | 2.851 | 31.492 |
Anterior 2/3 of tongue | 0.000 | 5.642 | 3.863 | 8.239 | 0.000 | 6.304 | 3.429 | 11.588 |
Overlapping lesion of tongue | 0.011 | 2.679 | 1.248 | 5.752 | 0.043 | 2.746 | 1.034 | 7.295 |
Tongue anterior, NOS | 0.000 | 4.109 | 2.925 | 5.772 | 0.000 | 6.362 | 3.880 | 10.431 |
