Figure 6 | Scientific Reports

Figure 6

From: The cyclophilin inhibitor NIM-811 increases muscle cell survival with hypoxia in vitro and improves gait performance following ischemia–reperfusion in vivo

Figure 6

Serum cytokine levels in female and male mice after hindlimb ischemia–reperfusion and treatment with NIM-811. (A–C) Serum IL-10, IL-27 and GM-CSF levels increased significantly in the serum of female mice treated with NIM-811 compared to control croup. (D) Serum IL-α level decreased significantly in the serum of female mice treated with NIM-811 compared to control group. (E) Serum IL-27 level increased significantly in the serum of male mice treated with NIM-811 compared to control croup. (F) Serum IL-α level reduced in the serum of male mice treated with NIM-811 compared to control croup. *P < 0.05, **P < 0.01 and ***P < 0.001.

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