Figure 4 | Scientific Reports

Figure 4

From: Studies on the mitochondrial, immunological and inflammatory effects of solvent fractions of Diospyros mespiliformis Hochst in Plasmodium berghei-infected mice

Figure 4

Immunomodulatory effects of Plasmodium infection and influence of treatment with dichloromethane fraction of Diospyros mespiliformis. (A) Serum TNFα significantly increased (P < 0.0001) maximally at 400 mg/kg of dichloromethane fraction of D. mespiliformis administration. (B) Serum interlukin (IL-1β) significantly (P < 0.0001) decreased in the DF-treated groups relative to the drug control while serum interlukin 6 (IL-6) of infected control and 100 mg/kg DF significantly (P < 0.0001) decreased relative to positive control (C). (D) IgG value increased maximally at 200 mg/kg of DF and (E) there is no significant difference in the IgM value in all the groups.

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