Table 3 Summary of quantified PTMs on histones H3 and H4*.
Histone | Modification | Control | Resistant | Susceptible |
|---|---|---|---|---|
H3 | K9ac | 15.8 ± 1.7 | 13.7 ± 0.7 | 15.9 ± 1.2 |
K9me | 24.5 ± 1.2a | 20.3 ± 0.8b | 22.5 ± 0.5ab | |
K9me2 | 16.3 ± 3.2 | 20.6 ± 1.0 | 16.0 ± 0.6 | |
K9me3 | 9.5 ± 0.7 | 10.8 ± 1.7 | 9.0 ± 1.9 | |
K14ac | 23.4 ± 1.4 | 21.3 ± 0.7 | 22.8 ± 0.7 | |
K18ac | 30.4 ± 1.0 | 28.7 ± 0.4 | 30.5 ± 0.5 | |
K18me | 1.3 ± 0.1 | 1.2 ± 0.1 | 1.3 ± 0.02 | |
K23ac | 30.8 ± 0.8 | 29.1 ± 0.8 | 30.5 ± 0.5 | |
K23me | 0.36 ± 0.02 | 0.32 ± 0.00 | 0.35 ± 0.01 | |
K27ac | 8.0 ± 0.0 | 7.2 ± 4.3 | 3.7 ± 1.9 | |
K27me | 38.9 ± 5.0 | 45.1 ± 6.5 | 36.4 ± 2.8 | |
K27me2 | 14.8 ± 6.3 | 14.9 ± 7.4 | 10.1 ± 4.5 | |
K27me3 | 14.1 ± 3.0b | 15.2 ± 3.9b | 30.8 ± 5.7a | |
K36ac | 6.7 ± 3.2 | 5.0 ± 1.2 | 7.4 ± 2.4 | |
K36me | 40.7 ± 3.1 | 44.7 ± 5.5 | 49.4 ± 3.6 | |
K36me2 | 7.9 ± 1.2 | 8.7 ± 0.4 | 8.7 ± 0.5 | |
K36me3 | 12.6 ± 4.7 | 11.9 ± 4.3 | 3.7 ± 1.1 | |
K37ac | 9.1 ± 2.0 | 14.9 ± 3.2 | 12.0 ± 0.1 | |
K37me | 16.1 ± 3.2 | 8.3 ± 2.8 | 14.3 ± 4.6 | |
K37me2 | 0.16 ± 0.00 | 1.3 ± 0.8 | 0 | |
K37me3 | 10.7 ± 6.4 | 5.4 ± 0.0 | 1.8 ± 0.8 | |
K56me | 1.6 ± 0.3 | 2.1 ± 0.2 | 12.0 ± 0.1 | |
K122ac | 0.33 ± 0.02 | 0.32 ± 0.01 | 0.31 ± 0.02 | |
K122me3 | 0.32 ± 0.00 | 0.34 ± 0.00 | 0 | |
H4 | K31ac | 12.4 ± 1.7 | 9.9 ± 2.8 | 10.5 ± 0.5 |
K31me | 7.0 ± 1.6 | 7.1 ± 3.0 | 8.2 ± 0.9 |