Table 4 Brain methylation quantitative loci (meQTLs) of the associated SNPs.
From: Genome-wide association study of psychiatric and substance use comorbidity in Mexican individuals
SNP | SNP position | CpG | CpG position | CpG gene | Beta | se | p-value |
|---|---|---|---|---|---|---|---|
(a) Subs | |||||||
rs4787483 | 16:29885447 | cg17945962 | 2:67793216 | – | 1.8154 | 0.3932 | 3.80e−06 |
rs2824496 | 21:19171547 | cg21278102 | 19:60482693 | HSBP1 (promoter) | − 1.2032 | 0.2537 | 2.10e−06 |
(b) Psych | |||||||
rs10208402 | 2:115203917 | cg09191731 | 16:22825045 | HS3ST2 | 1.3293 | 0.2874 | 3.73e−06 |
rs13074870 | 3:177363666 | cg26017930 | 1:2232165 | SKI (Promoter) | 1.2075 | 0.2555 | 2.28e−06 |
cg13906646 | 6:166892920 | RPS6KA2 | − 1.2005 | 0.2555 | 2.61e−06 | ||
cg26559829 | 16:85206154 | − 1.1834 | 0.2555 | 3.61e−06 | |||
cg06852461 | 1:207975183 | C1orf132 | − 1.1825 | 0.2555 | 3.67e−06 | ||
cg04144365 | 2:188483529 | − 1.2275 | 0.2555 | 1.55e−06 | |||
cg06709297 | 2:10302453 | C2orf48 | − 1.2226 | 0.2555 | 1.70e−06 | ||
cg07046426 | 2:237623902 | 1.1832 | 0.2555 | 3.62e−06 | |||
cg10464312 | 2:66672687 | MEIS1 | 1.1709 | 0.2555 | 4.57e−06 | ||
cg06055229 | 5:124077965 | ZNF608 | − 1.1714 | 0.2555 | 4.53e−06 | ||
cg06445944 | 5:67586927 | PIK3R1 | − 1.1734 | 0.2555 | 4.36e−06 | ||
cg14196170 | 6:32063594 | TNXB | − 1.2095 | 0.2555 | 2.19e−06 | ||
cg26577169 | 6:166401611 | LINC00602 | − 1.1663 | 0.2555 | 4.98e−06 | ||
cg16107105 | 7:150646703 | KCNH2 | 1.1754 | 0.2555 | 4.20e−06 | ||
cg09759289 | 8:28223456 | FBXO16 | − 1.1725 | 0.2555 | 4.43e−06 | ||
cg26280695 | 10:106072439 | ITPRIP | 1.1991 | 0.2555 | 2.68e−06 | ||
cg03447547 | 14:94577038 | IFI27 | 1.2104 | 0.2555 | 2.16e−06 | ||
cg19733938 | 14:102510359 | DYNC1H1 | − 1.1678 | 0.2555 | 4.84e−06 | ||
cg23909173 | 14:94451388 | − 1.1927 | 0.2555 | 3.03e−06 | |||
cg05333442 | 16:58533742 | NDRG4 | − 1.1678 | 0.2555 | 4.84e−06 | ||
cg00080125 | 17:59490612 | C17orf82 | 1.1733 | 0.2555 | 4.37e−06 | ||
cg00591333 | 17:79109909 | AATK | − 1.1854 | 0.2555 | 3.48e−06 | ||
cg19919217 | 17:38248104 | THRA | − 1.2131 | 0.2555 | 2.05e−06 | ||
cg14771451 | 22:18508297 | MICAL3 | − 1.1858 | 0.2555 | 3.45e−06 | ||
rs7701154 | 5:77716621 | cg18281939 | 5:77783894 | LHFPL2 | − 1.1750 | 0.2495 | 2.49e−06 |
(c) Com | |||||||
rs12747494 | 1:91944137 | cg25100604 | 2:70314405 | PCBP1 (Promoter) | − 1.3127 | 0.2844 | 3.91e−06 |
cg08057136 | 2:207506976 | – | − 1.3785 | 0.2844 | 1.25e−06 | ||
cg27519869 | 7:92219804 | FAM133B (Promoter) | − 1.3326 | 0.2844 | 2.78e−06 | ||
rs953855 | 2:77123866 | cg13294780 | 4:140005755 | ELF2 | − 1.1535 | 0.2494 | 3.74e−06 |
rs1039201 | 3:11731029 | cg10087374 | 8:21960455 | FAM160B2 | 1.1584 | 0.2500 | 3.61e−06 |
