Table 1 Baseline characteristics of patients and clinical response to the docetaxel plus carboplatin regimen.

From: Activity of docetaxel, carboplatin, and doxorubicin in patient-derived triple-negative breast cancer xenografts

Patient and disease feature from the diagnostic core

N = 9 (%)

Age (year)

˂50

4 (45%)

 ≥ 50

5 (55%)

Menopausal status

Pre

4 (45%)

Post

5 (55%)

Clinical T-stage

T1

1 (11%)

T2

5 (55%)

T3

2 (23%)

T4

1 (11%)

Clinical N-stage

N0

2 (23%)

N1

6 (66%)

N2

1 (11%)

N3

0 (0%)

Symmans class

pCR

3 (33%)

RCB-I

1 (11%)

RCB-II

3 (33%)

RCB-III

2 (23%)

Clinical response (MRI)

Complete response

2 (23%)

Minor response

5 (55%)

Partial response

1 (11%)

Progression disease

0 (0%)

Stable disease

1 (11%)

Ki 67 expression

˂50

1 (11)

 ≥ 50

8 (89%)

Histologic grade

G1

0 (0%)

G2

2 (23%)

G3

6 (64%)

No data

1 (11%)

Germline homologous recombination mutation

BRCA wt

6 (66%)

BRCA mut

2 (22%)

PALB2 mut

1 (11%)

Current status (the last follow-up date)

Recurrence and death

2 (22%)

Recurrence and alive

1 (11%)

Alive and no recurrence

6 (66%)

  1. MRI magnetic resonance imaging, pCR pathological clinical response, RCB residual cell burden, T tumor, N nodes, G grade.