Table 3 PDMX1001/niclosamide trough and peak concentration.

From: Phase Ib trial of reformulated niclosamide with abiraterone/prednisone in men with castration-resistant prostate cancer

Patient

Level

Time

Concentration (ng/mL)

Concentration (µM)

002

Trough

7.5 h post dosing

100.05

0.306 (trough)

002

Peak

1 h post dosing

70.04

0.214 (peak)

004

Trough

8 h post dosing

162.16

0.496 (trough)

004

Peak

1 h post dosing

170.38

0.521 (peak)

005

Trough

6.5 h post dosing

212.06

0.648 (trough)

005

Peak

1 h post dosing

236.41

0.723 (peak)