Table 1 Description of the MDCS-CVA and two random samples of the study population.

From: Methodological considerations for identifying multiple plasma proteins associated with all-cause mortality in a population-based prospective cohort

Characteristic

Total study population

Random sample 1

Random sample 2

P-value*

Number of subjects

3918

1963

1955

 

Number of deaths

974

491

483

 

Cause of death (%)

Cancer

41.8

41.6

42.0

 

Cardiovascular

29.1

28.9

29.2

 

Neurological

6.1

6.1

6.0

 

Respiratory

5.8

5.7

5.8

 

Age, years

57.2 (5.9)

57.4 (5.9)

57.1 (5.9)

0.17

Male gender (%)

40.4

41.9

38.8

0.05

Body mass index, kg/m2

25.6 (3.9)

25.6 (3.8)

25.5 (4.0)

0.62

Current smoking (%)

25.8

27.2

24.5

0.12

University/college degree (%)

11.8

11.6

12.1

0.95

Prevalent diabetes mellitus (%)

3.5

3.4

3.5

0.84

History of hypertension (%)

61.9

61.5

62.3

0.60

C-reactive protein, mg/dL#

1.3 (0.7–2.7)

1.4 (0.7–2.8)

1.3 (0.6–2.7)

0.04

LDL-cholesterol, mmol/L

4.2 (1.0)

4.2 (1.0)

4.2 (1.0)

0.09

HbA1c, %#

4.8 (4.5–5.1)

4.8 (4.5–5.1)

4.8 (4.5–5.1)

0.94

  1. *Mean (standard deviation, SD) are shown unless otherwise noted. Chi-square test (categorical variables) and ANOVA (continuous variables) used to test differences in characteristics between random sample 1 and 2.
  2. #Median (interquartile range) and P-value from ANOVA using ln-transformed variable due to non-normal distribution.
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