Table 2 Sample characteristics according to methylation of 1F region NR3C1 gene.

Characteristic	Total		Methylation				p
	Total		No		Yes
	N	(%)	N	(%)	N	(%)
Gender
Male	60	21.0	50	17.5	10	3.5	0.009*
Female	225	79.0	148	52.0	77	27.0
Age (years)
20–40	125	43.8	87	30.5	38	13.3	0.967
41–60	160	56.2	111	39.0	49	17.2
Marital status
Single	70	24.6	55	19.3	15	5.3	0.057
No single	215	75.4	143	50.2	72	25.2
Education
Basic education	240	84.2	167	58.6	73	25.6	0.926
Higher education	45	15.8	31	10.9	14	4.9
Working
Yes	151	53.0	103	36.2	48	16.8	0.623
No	134	47.0	95	33.3	39	13.7
Income
Non-low income (≥ $5.00/day)	81	28.4	58	20.4	23	8.0	0.623
Low income (< $5.00/day)	204	71.6	140	49.1	64	22.5
Tobacco consumption
No	261	91.6	176	61.8	85	29.8	0.014*
Yes	24	8.4	22	7.7	2	0.7
Alcohol consumption
No	201	70.2	125	43.9	75	26.3	0.000*
Yes	84	29.8	73	25.6	12	4.2
Weekly drinking
< 7 drinks	64	76.2	53	63.1	11	13.1	0.438
> 7 drinks	20	23.8	18	21.4	2	2.4
Physical activity
Yes	95	33.3	69	24.2	26	9.1	0.413
No	190	66.7	129	45.3	61	21.4
Leisure activity
Yes	132	46.3	97	34.1	35	12.3	0.172
No	253	53.7	101	35.4	52	18.2
Self-rated health
Good or very good	145	50.9	105	36.8	40	14.0	0.273
Regular or poor	140	49.1	93	32.6	47	16.5
Depression
BDI-II < 17	194	68.1	136	51.3	58	21.9	0.142
BDI-II ≥ 17	71	24.9	43	16.2	28	10.6
Not available^#	20	7.0
Body mass index—BMI
No overweight	96	33.7	59	20.7	37	13.0	0.036*
Overweight	189	66.3	139	48.8	50	17.5
Vitamin D
Sufficiency	264	92.6	185	64.9	79	27.7	0.434
Deficiency	21	7.4	13	4.6	8	2.8
High cortisol levels
No	270	94.7	185	67.0	85	30.8	0.107
Yes	6	2.1	6	2.2	0	0.0
Not available^#	9	3.2
Total	285	100.00	198	69.50	87	30.50

BDI-II Beck Depression Inventory-II, BFIS Brazilian Food Insecurity Scale, FNS Food and Nutrition Security, FNiS Food and Nutrition Insecurity, BMI Body Mass Index. ^#Not available (not considered in the statistical calculations). Categorical variables presented in relative (%) and absolute (n) frequencies. Quantitative variables presented in medians and interquartile ranges (IR), according to normality (Kolmogorov–Smirnov test); * p value: Mann–Whitney U or chi-square, at 5% significance (p < 0.05).

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