Table 5 Multinominal linear regression analyses of LGMN score by lesion type and HLA-DR.

White matter lesions

LR χ²

F_{df 2} = 23.5, p < 0.001

F_{df 2} = 14.9, p = 0.001

F_{df 2,48} = 8.8, p = 0.001

Active

8

13.3%

4.00

[2.22,6.22]

 < 0.001

2.70

[1.17,4.46]

0.001

1.60

[−0.53,3.87]

0.129

Chronic active

17

28.3%

1.60

[0.45,2.86]

0.008

1.60

[0.41,2.91]

0.011

1.50

[−0.29,3.64]

0.108

Chronic inactive*

35

58.3%

0*

–

–

0*

–

–

0*

–

–

Gray matter lesions

LR χ2

F_{df 3} = 7.6, p = 0.056

F_{df 3} = 3.7, p = 0.154

F_{df 3} = 1.6, p = 0.662

Type 1—leucocortical

11

17.7%

1.29

[−0.86,3.56]

0.248

1.74

[−0.45,4.05]

0.126

0.00

[−3.26,3.26]

 < 1

Type 2—intracortical

16

25.8%

-1.47

[−3.42,0.41]

0.129

0.52

[−1.35,2.45]

0.593

1.39

[−1.21,4.31]

0.322

Type 3—subpial

28

45.2%

-0.90

[−2.56,0.75]

0.283

-0.01

[−1.67,1.72]

0.990

0.38

[−2.06,3.02]

0.770

Type 4—throughout cortex*

7

11.3%

0*

–

–

0*

–

–

0*

–

–

HLA-DR

LR χ²

F_{df 2} = 35.7, p < 0.001

F_{df 2} = 41.7, p < 0.001

F_{df 2} = 8.0, p = 0.018

Inactive

74

66.1%

0*

–

–

0*

–

–

0*

–

–

Reactive

29

25.9%

2.28

[1.35,3.28]

 < 0.001

2.64

[1.67,3.7]

 < 0.001

1.39

[0.07,2.83]

0.064

Active, amoeboid

9

8.0%

3.27

[1.83,4.8]

 < 0.001

3.22

[1.82,4.71]

 < 0.001

2.18

[0.43,3.91]

0.009