Table 1 Demographics and clinical characteristics.

From: Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women

Characteristics

Control

PE

PEsuper

Eclampsia

HELLP

Sample size, n

693

342

61

74

112

Maternal age, y, mean (± SD)

24.4 (± 6.2)

25.2 (± 6.8)

31.1 (± 6.9)a

20.5 (± 6.1)a

27.0 (± 6.7)a

SBP, mmHg, mean (± SD)

117 (± 12)

156 (± 19)a

166 (± 28)a

159 (± 21)a

154 (± 21)a

DBP, mmHg, mean (± SD)

75 (± 9)

105 (± 13)a

108 (± 14)a

108 (± 16)a

101 (± 13)a

Proteinuria, n (%)

Negative

693 (100)

0 (0.0)

0 (0.0)

2 (2.7)

7 (6.3)

1 +

104 (30.4)

28 (45.9)

11 (14.9)

13 (11.6)

≥ 2 +

238 (69.6)

16 (26.2)

43 (58.1)

85 (75.8)

Missing

0 (0.0)

17 (27.9)

18 (24.3)

7 (6.3)

Primigestas, n (%)

300 (43.3)

180 (52.8)a

14 (23.3) a

54 (73.0)a

46 (41.4)

Gestational age at delivery, w, mean (± SD)

38.8 (± 3.1)

37.2 (± 3.0)a

35.8 (± 3.5)a

36.2 (± 3.6)a

34.3 (± 4.0)a

Number of antenatal care visits, mean (± SD)

5.9 (± 2.8)

6.2 (± 2.3)

6.1 (± 2.9)

4.5 (± 2.5)a

5.3 (± 2.3)a

Family history of

Chronic hypertensionb

238 (35.5)

178 (56.9)a

46 (80.7)a

32 (46.4)

55 (49.6)a

Preeclampsiac

22 (3.8)

41 (15.9)a

5 (10.9)a

12 (21.0)a

8 (8.3)a

Eclampsiac

7 (1.2)

11 (4.4)a

3 (6.5)a

5 (8.8)a

2 (2.1)

  1. SBP/DBP systolic blood pressure/diastolic blood pressure.
  2. PEsuper: chronic hypertension with superimposed preeclampsia.
  3. ap < 0.05 for comparison with the control group.
  4. bIf at least one first degree relative has the disease.
  5. cIf the mother had had the disease.