Figure 3
CFD simulated shear rates and shear rate gradients in eccentric (A–D) and concentric (E–H) stenoses geometry under various stenosis level. (A and E) The streamlines of blood flow in the eccentric and concentric stenosis microfluidic channels for S = 70% (top) and 90% (bottom) respectively. The representative streamline of a platelet trajectory was colored by shear rate values. (B and F) Peak shear rate γmax exponentially correlates with the input stenosis level S for both eccentric and concentric stenoses respectively. Note that the concentric γmax is higher than that of eccentric stenosis channel. The shear rate γ (C and G) and shear rate gradient γ′ (D and H) distribution is plotted along a sample streamline 1 µm above the stenosis apex spanning the shear acceleration (x = −100 to 0 µm) and deceleration (x = 0–100 µm) zones. Note that γmax and γ’max occur at the same location as in Fig. 2.
